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The challenges associated with cancer treatment range from a lack of understanding of fundamental pathogenic mechanisms to practical experimentation limitations.
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This kind of experimentation has major limitations.
"While the system gives individuals the power of choice and allows for innovation ands experimentation a major limitation of the free market economy is that it has no mechanism to reduce the disparity between the haves and have-nots," he said.
These direct and indirect effects can be evaluated only by using controlled experimentation [32], albeit with limitations.
Since there are limitations to experimentation with humans, the use of animal models is necessary when testing these strategies.
It provides a view of the functioning of the system although its internal processes still cannot be clarified because of limitations on experimentation on large animals such as ruminants.
Here we highlight technical and theoretical foundations as well as recent advances and opportunities in this area, and we review in detail the known caveats and limitations of optogenetic experimentation in the context of addressing these challenges with closed-loop optogenetic control in behaving animals.
Alan Moore is a man who's always been fond of experimentation and breaking through the limitations of whatever medium he finds himself working in.
Taking into consideration factors such as cost, ethics, and technical limitations of animal experimentation, researchers moving from bench to bedside are still in search of a scientific bridge between simple cell culture and complex in vivo models.
However, an important limitation of the experimentation with educational interventions is that it is not possible to guarantee that participants have received the content of the intervention, as it could be done if it were a pill, for instance.
The limitations of biological experimentations in this system can be overcome by computational modelling, which is proving to be a valuable tool to shed light on the function of not only this system [ 35- 37], but other signalling networks too [ 38].
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