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Exome sequencing of these experimentally progressed cell lines recapitulates a list of genes previously reported to be involved in CRC tumorigenesis.
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Moreover, the pyrE system requires the correction of the pre-generated pyrE mutation before progressing experimentally – increasing the effort and time required to generate mutant strains13.
The degree to which the sequences of these genes are accurately defined in our databases will largely determine the ease with which we can progress experimentally.
The models for each amine substrate showed excellent agreement with experimentally determined progress curves over a range of operating conditions.
These workers studied groups of animals with experimentally-induced FMD and measured temperatures (primarily around the coronary band) as disease progressed.
Twenty sheep experimentally exposed to MAP and 10 controls were monitored for 2.5 years during which the condition progressed, resembling natural disease development.
Although insights into DNA repair have progressed at an impressive pace, especially in the past decade, an understanding of the mechanisms of mutagenesis — a phenomenon that, as mentioned earlier, was demonstrated experimentally before discovery of the structure of DNA — has lagged.
As the cultures progressed, however, these NHK colonies gradually lost their momentum to expand due to the loss of feeder cells (Figure 5F), which was confirmed experimentally (Figure 5C and E).
Moreover, it was experimentally reported that benign-appearing skin and soft tissue infections caused by MRSA can progress rapidly to potentially fatal diseases [18].
Still progressing.
Its destruction by electrons has been controversial for many years, but recently there has been much progress both experimentally and theoretically in the understanding of electron-H3+ recombination.
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