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Hexyl ester of 5-ALA (5-ALA-Hex) (Hexvix®) has gained marketing authorization for the photodiagnosis (PD) of bladder cancer [30, 31] and is experimentally exploited for the treatment of cervical cancer and severe acne [32 34].
The virtually invariant spatiotemporal cell division pattern can be experimentally exploited to detect subtle defects in the stringent control of cell divisions that result in ectopic cell production (van den Heuvel 2005; Kirienko et al. 2010).
To determine whether size-selective harvesting induced genetic changes in the experimentally exploited zebrafish populations, we used 371 genomewide, evenly distributed single nucleotide polymorphisms (SNPs) that were chosen from a previously analyzed wild zebrafish dataset (Whiteley et al. 2011) in 502 individuals (Supporting Information S6).
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It is generally recognized that optimal control algorithms are key tools needed for further advances in experimentally exploiting these quantum systems for simulation as well as for computation [23 26].
DOI: http://dx.doi.org/10.7554/eLife.08961.014 To address this experimentally we exploited the fact that BiP produces characteristic conformation-dependent proteolytic patterns in low concentrations of proteinase K (Kassenbrock and Kelly, 1989; Wei et al., 1995).
New hypotheses can now be addressed experimentally by exploiting the expanding toolbox of reverse genetics, such as insertion mutants combined with targeted metabolic profiling, and by reverse biochemistry using collections of recombinant proteins and medium throughput screening of substrate collections [ 58].
The unique properties of one-dimensional (1D) Fibonacci chains of dielectric layers are experimentally demonstrated and exploited for the design of new mirrors with multiple reflection spectral windows.
Probe axial position detection is an added benefit of intensity pattern fitting that has not been exploited experimentally.
Despite the absence of a naturally occurring viral infection for C. elegans, the model is now being exploited experimentally to study the basic aspects of virus-host interplay.
Together with available empirical data, our results indicate that allele interaction can be exploited experimentally to identify and explain intricate intra- and inter-locus feedback relationships in eukaryotes.
Recombination can be exploited experimentally to map loci associated with biological traits: indeed, the construction of linkage maps is among the oldest activities in genetics (Sturtevant 1913).
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