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The abovementioned parameters were experimentally defined; therefore, one concern was their sensitivity.
We also found that overexpression of the enzyme Map1 negatively affects the expression of experimentally defined mRNA targets.
Molecular dynamics simulations have been used to gain insight into conformational changes relative to an experimentally defined structure [18], [19].
We propose deriving multiple factors, based on human cancer gene expression studies, from an experimentally defined signature.
Specifically, haplotypes were determined in silico and were compared with the experimentally defined haplotypes from the haploid cell lines.
We experimentally defined the optimal phosphorylation motif of the kinase OST1 by screening a semi-degenerate combinatorial peptide array [47].
From an experimentally defined gene expression signature we use statistical factor analysis to generate multiple quantitative factors in human cancer gene expression data.
The adult dose of Al(OH 3 (1 mg) was weight-adjusted to 0.25 mg for immunization of 1-wk-old mice respectively, as previously experimentally defined [22].
We further analyzed our experimentally defined set of 180 RBPs for the occurrence of protein domains annotated by the Pfam database [23].
Lengths of 23S rRNA genes were identified by using experimentally defined 23S rRNA sequences from the closest relatives available and verified by 2° structure analysis based on minimizing free energy, using RNAstructure [12] and Rnaviz [13], with experimentally defined 23S rRNA or the consensus 23S rRNA models [14] used for reference.
Motif3 matched the experimentally defined motif PIIATGAPB, which is responsible for light-activated gene expression [ 75].
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