Sentence examples for experimental stringency from inspiring English sources

We attribute these discrepancies to the experimental stringency of the current study, which was performed under conditions designed to minimize potential genetic drifts.

Extrapolation of our chromosome 19/20 results suggests that under similar experimental and computational stringency we would expect in the human genome just over 2,000 ARORs that would be classified as L1 and around 6,300 as L2.

The position of the biomarker in the spectrum between research tool and clinical end point dictates the stringency of experimental proof required to achieve method validation (Lee et al, 2007).

By using such stringency in experimental design, it will likewise be beneficial to study the associations between DNA methylation and splice variant formation across tissues during development, maturation, and aging in a variety of insect species with different life-history dynamics and behaviors.

These databases typically contain literature-derived interactions curated with different degrees of stringency, and based on experimental publications under different experimental conditions using different cell types.

Outcomes of experiments depend not only on experimental design but also on the stringency of conditions of the experiments: for example, too stringent conditions can lead to false negative interactions, as opposed to false positive results obtained from experiments that were not stringent enough.

Likely, these results reflect substantial differences in experimental design and conditions, including cDNA library origin, plant background, stringency of stress conditions, plant species, setting up and processing of microarrays.

The stringency of this filter can be modified depending on experimental needs.

Perhaps because of the stringency with which we performed both the microarray analysis and the experimental validation, even here the small changes predicted by microarray were consistently seen with the qRT-PCR data, although the quantitative correlation was not as strong overall as for data showing larger changes.

To further increase the inference stringency and to down-select a smaller number of genes for future experimental validation, we applied the following criterion: the expression of a gene must show statistically significant difference between the treated and the control at both duplicate spots to be inferred as a differentially expressed gene.

To create the core dataset, we used intervals supported by at least one low stringency (25% FDR) and one high stringency (1% FDR) dataset from independent experimental techniques.