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While they use the Discussion to argue their point, it seems that a revised Results text, with some experimental revision may alter the conclusions made in the Discussion substantially.
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No major experimental revisions are required but comments and concerns were raised by all three reviewers primarily in two areas: (1) relevant considerations that are not discussed in the text, and (2) limitations of the very simple theoretical model.
AC: Hypothesis and experimental design and revision.
ARJP contributed to experimental design and revision of manuscript.
RJ assisted with project planning and experimental design and revision of the manuscript.
IM and SU contributed to conception of the study, experimental design, and revision of manuscript.
NS, AJM, and SJD conceived the experiments and wrote the paper, with critical experimental and intellectual revisions from SDM and RMA.
We have addressed each of these five points with additional experimental evidence, and the revision includes new supplementary figures and text revisions as needed to address each point.
Z.L. aided in experimental procedures and paper revision.
JZ contributed to the experimental design and manuscript revision.
MC participated in the animal experimental design and manuscript revision.
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CEO of Professional Science Editing for Scientists @ prosciediting.com