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Detailed experimental profiling of reactions of less than 300 nl total volume is achieved using the platform demonstrating the dynamic range to be 4 order logs and consistent instrument sensitivity.
While experimental profiling of the genes has been carried out previously [ 16, 17], the availability of large-scale gene expression data allows one to perform such studies in a faster and less expensive manner.
Recent advances in experimental profiling of genome-wide signals such as histone modifications and DNase I hypersensitivity sites allow scientists to develop better computational methods to enhance motif discovery.
Experimental profiling of mRNA structure at genome scale both in vitro[ 6, 11- 13] and in vivo[ 14] has confirmed regulatory roles of mRNA secondary structure in various organisms.
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The experimental profiles were modeled successfully using this approach.
The calculated data matched the experimental profiles well.
The experimental profiles could be explained by the existing theories.
The latest builds of Chrome (version 14 in the Canary channel) feature a new, experimental profile switching and creation icon.
The predicted deposition rate profiles obtained using both schemes are compared to the experimental profiles.
A comprehensive experimental profile is designed to obtain the test datasets.
In both cases, the experimental profiles were fitted to a modified first-order kinetic model.
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