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Several experimental pathways have been reported through which such polymorphs are experimentally achievable.
This concept allows complex experimental pathways to be fitted with only two adjustable parameters, including the closure of scanning loops without any pumping effect.
To account for differences in functional clustering of genes in the experimental pathways and in the random control gene sets, we compared the distance between genes on the same chromosome [see Additional file 4: Figure S2].
The experimental and control sets were distributed similarly but, due to the smaller number or paired genes for the experimental pathways, there were fewer gene pairs at long distances across the chromosomes (particularly > 10 Mb).
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The gene to structure endeavor faces intrinsic challenges at several steps in the experimental pathway.
Pathway inference by CoGAPS was predictive across a heterogeneous set of experimental pathway manipulations, i.e., transcriptional responses triggered either by overexpression of EGFR, NF-kB/p65 or mutant HRAS, or those induced by addition of serum to culture media.
By combining known experimental pathway information on B cell signaling, and the network derived through a shortest path analysis, we could generate the CH1 cell-specific signaling axis responsible for driving G1 arrest.
If such treatments fail or behave differently between different animal species and humans, developing a revised research approach that attempts a hypothesis-driven experimental pathway is difficult since few scientific hints or guiding details are provided from the initial animal-based experimental designs.
The utility of this proteome-wide approach to exploring environmental exposures is that a broad screen in tandem with quantitative analysis can reveal a broader picture of the overall exposure effects than using traditional, targeted methods; however, validation and confirmation remain critical steps in this experimental pathway.
These findings suggest that thin-film growth of pharmaceutical systems in general should be explored, where poor aqueous dissolution represents a key limiting factor in pharmaceutical applications, and illustrate the experimental pathway for determining the physical properties of a pharmaceutically relevant SIP.
A correlation is also established between the optimized adsorption geometry and experimental reaction pathways.
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