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Compared with experimental knowledge, for most interactions in the gene regulatory network the sign, i.e. activation, repression or no-interaction was reasonably well reproduced.
Moreover, our results showing high positive coordination with no negative coordination among HCGs of the same group and high negative coordination with no positive coordination between HCGs of different groups within the same network imply that our Gene Coordination approach can identify HCGs groups and networks without any prior experimental knowledge for their existence.
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Eisen proposed a conceptual approach for predicting protein function using a phylogenetic tree together with available experimental knowledge of proteins.
In this review, we summarize the experimental knowledge currently available for the TCS of the C. glutamicum type strain ATCC 13032 and we present an in silico analysis of TCS in Corynebacterium species for which complete genome sequences are available.
In standard histories Hunter may be an enlightenment hero; in Mantel's reimagining, he is somebody much stranger, stabbing and infecting himself out of intellectual curiosity, twisted and tormented by his thirst for experimental knowledge.
The published assessments that probe for experimental knowledge relevant to each category of difficulty (Table 1, I V) used in this study will be referred to as the shrimp, the drug, and the bird assessments, published by the College Board (2006), SRI International (2003), and the College Board (2009), respectively.
Altogether, these advances in the fundamental and experimental knowledge on OA may allow for the generation of improved, adapted therapeutic regimens to treat human OA.
This amounts to a trade-off between the requirement of discrete models for less detailed experimental knowledge and applicability to larger systems, and the greater, subtler and probably more realistic insight of quantitative models.
In this section, we describe the procedure for constructing the mathematical model based on the existing experimental knowledge.
The experimental knowledge is immense.
Projects will be interrupted, and experimental knowledge will be lost.
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