Sentence examples for experimental hurdle from inspiring English sources

We conclude that, in spite of significant computational advances, a major experimental hurdle related to the evaluation of the penetrability of sub-resolution pores, is blocking the way ahead.

To address this significant experimental hurdle and the need to accurately measure the viscoelastic properties of soft materials at high strain-rates (103 108 s−1), we present a minimally invasive, local 3D microrheology technique based on inertial microcavitation.

Here, we bypass this experimental hurdle by employing subtle synthetic derivatives of naturally occurring side chains in combination with concatenated subunits to probe the inter- and intra-subunit atomic determinants that control the onset and cooperativity of slow inactivation in Kv channels.

A number of technological and experimental hurdles remain that must be overcome in the design, execution and interpretation of experiments aimed at detailing the functional roles of accessory subunits and associated proteins in the generation of native neuronal Kv channels.

Other, less tangible aspects of druggability are much harder to predict, including any "experimental hurdles" and unforeseen adverse effects, until trialed [ 57].

Given these experimental hurdles, we argue that metabolic models derived from bioinformatic analyses offer an especially attractive starting point for unraveling the interesting physiology of A. ferrooxidans.

We set out to overcome these experimental hurdles by combining into a single vector all of the essential elements for recombinant protein expression in both bacteria and yeast in a one-step, ligation-independent process.

While many of the original experimental and data analysis hurdles have been addressed, a framework in which one can assess the quality control and data adjustment measures taken after obtaining accurate gene expression estimates was lacking.

This makes comparisons between studies unreliable and is an unnecessary hurdle in extrapolating experimental results to clinical reality.

Japan's Monju experimental fast-breeder reactor faces one last hurdle before restarting 14 years after an accident and a botched coverup shut it down: An OK from the governor of Fukui Prefecture, which hosts the reactor.

Unfortunately, databases do not capture the textual passages linked to the experimental evidence and this represents a significant hurdle to the development of text-mining suites.