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N. benthamiana is the favoured experimental host for agrobacterium-mediated transient expression and is susceptible to PSbMV.
All experimental host colonies were haphazardly selected, tagged, mapped and randomly assigned one of the five treatments.
Consistent with this, our data demonstrate that the microbe elicits a reproducible cellular inflammatory response in the lungs and airways of this experimental host.
Previous studies using tomato, the preferred experimental host for PSTVd, have shown that PSTVd replicates in the nucleus and that strands accumulate to significantly higher levels than strands [6].
Of note, one study did not illustrate a detectable impact of worm carriage on a rodent model of cerebral malaria, suggesting that various experimental host parasite combinations can yield different results [23].
These results stand in contrast to previous in vitro studies suggesting that the capacity for genetic change of SLEV may be less than that of WNV in mosquitoes, yet in cell culture studies SLEV became highly adapted to the experimental host while here it did not [11].
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This contrasts markedly with previous work on the evolution of cooperation, in which dispersal between environmental patches or transmission between hosts is controlled by the experimenter and experimental hosts are essentially treated as rather advanced test tubes.
Recovery from viral symptoms was observed in natural and experimental hosts.
A large number of plant viruses can successfully infect N. benthamiana, as one of the most widely used experimental hosts in plant virology.
Tests in experimental hosts showed that it was a true viral recovery, in that the virus was absent and the recovered tissues could not be infected.
Kuru, a familial degenerative disease of the nervous system occurring in a restricted area of the Highlands of New Guinea, has apparently been transmitted to chimpanzees, but not to any other of the many experimental hosts tried.
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