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Based on the experimental evolutions a macroscopic model is presented, describing the relation between the considered general process parameters.
Amplification of the HXT6/7 locus has been found in other experimental evolutions (Brown et al., 1998; Gresham et al., 2008; Kao and Sherlock, 2008).
SUL1 gene amplification was a common adaptation in continuous cultures under sulfate limitation, occurring in 15 of 16 adapted clones from various experimental evolutions [ 4].
Despite the recurring emergence of aneuploidy in a variety of natural and experimental evolutions, the absence of detectible aneuploidy in other systems was notable.
Amplification of the HXT6/7 locus has been found in other experimental evolutions (Brown et al. 1998; Gresham et al. 2008; Kao and Sherlock 2008)." 5) Many wild S. cerevisiae strains are clumpy and loss of clumpiness is likely a lab-adapted trait.
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