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However, their full developmental role remains uncertain owing to limited success in their identification and experimental elimination.
Experimental elimination of c-kit in mice mobilized with plerixafor or anti-VLA-4 resulted in a negative effect of mobilization [ 61].
In this case, experimental elimination of these forces should be sufficient to speed up the process even in the absence of Cdk1 activity.
Experimental elimination of S1P1 receptors leads to impaired mobilization after CXCR4 inhibitors in mice, while intravenous administration of S1P1 agonists induces the opposite effect [ 52, 53].
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This conclusion is in good accordance with the available experimental data: (1) elimination of the inhibitory vCH-cell eliminates the preference of the FD-cell for small objects [28].
In each STP simulation, over the entire experimental period, DOC elimination was 95%to98%8%.
From the experimental, the highest elimination of the DR81 was 95. 5% after 30 min incubation at pH 5, temperature 40 °C, ABTS 0.2 mM, and initial concentration of DR81 50 mg L−1 in the presence of 0.2 U mL−1 of the laccase.
In fact, our studies suggest that other receptors may exist because, in some of our experimental systems, the elimination of IL-13Rα2 only partially abrogated the specific Chi3l1/YKL-40/BRP-39 effectoresponsese.
In vivo, it has been suggested that SOX2+ve cells could generate new endocrine cells in experimental endocrine cell elimination models, where limited regeneration was observed (Fu et al., 2012; Fu and Vankelecom, 2012), although these studies were correlative and did not involve fate-mapping.
Extrapolations to infinity (AUCinf) were obtained by dividing the concentration at the last experimental points by the elimination constant (Ke).
On the other hand, we have found that normalization is absolutely required for the elimination of experimental variations.
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