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Novel high-throughput technologies for directed evolution enable experimental coverage of an impressive number of sequences.
We present a detailed study of the various stable configurations that hydrogen can adopt upon the surfaces at coverage ratios starting below 1.0, up to the point of their experimental coverage ratios, and beyond.
Using this term in an equilibrium adsorption isotherm then allows standard free energies of adsorption and derived quantities to be properly calculated from experimental coverage or surface excess measurements.
As the immersion time increases, the height of the particle increases, and this shape change results in the experimental coverage getting closer to the theory curve, in which we assume the particles to be perfect hemispheres, as shown in Figure 4b.
However, it is difficult to draw conclusions based solely on these raw numbers because the experimental coverage space of PPIs is highly unbalanced across these species.
These results in high false negative rates and low experimental coverage of the interactomes.
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For PVAP, the experimental surface coverage values at different temperatures were fitted to various isotherm models including Langmuir, Temkin, Frumkin, and Flory–Huggins.
We also estimated the proportion of each chromosome sequence for which the experimental read coverage is low (≤10).
Other applications could be derived from the establishment of virtual HTS profiles; for example, the filtering of small insertions/deletions and rearrangements, as well as for the identification of copy number changes when combined with the analysis of experimental HTS coverage.
Progress in measurement techniques and scaled-down experimentation has raised the experimental throughput and coverage to which isotope-labeled tracers in the metabolism are quantified (Fan and Lane, 2008).
Mr. Nickerson's insurer considered the treatments experimental and denied coverage.
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