Sentence examples for experimental blockade from inspiring English sources

Consistent with this role, the most prominent effect of experimental blockade of GLP-1 signaling is an increase in blood glucose.

Experimental blockade of IL-6 signaling with monoclonal antibodies was effective in suppressing chronic intestinal inflammation in mouse models, which suggests IL-6 as a potential therapeutic target in management of IBD [30, 31].

An outstanding difference between our modeling and experimental results is that experimental blockade of the M-current did not produce persistent firing as in our model.

Experimental blockade or deletion of platelet receptors interferes with the TCIPA process, resulting in significantly decreased metastasis [ 8, 9].

PD-1 is upregulated on HIV-specific CD8+ T cells and experimental blockade of PD-1 enhances proliferation and cytokine production 54, 55.

The colors show the number of charge states in the bias window for a given gate voltage and exhibit the typical diamond shapes also seen in experimental Coulomb blockade measurements.

Although macrophage infiltration is observed in cisplatin-induced experimental AKI, blockade of macrophage trafficking to the kidney did not prevent renal injury [ 15].

In the kidneys, EMT of tubular epithelial cells is a mechanism by which renal fibroblasts are generated, and the importance of EMT has been demonstrated in experimental models, where blockade of EMT attenuates renal fibrosis.

More recently, β-amyloid deposition was associated with RGC death in experimental glaucoma and blockade of the β-amyloid pathway reduced glaucomatous damage.

Despite the increased investment in transmission-stage parasites observed for some clones in response to IL-10R blockade, experimental enhancement of immunopathology incurred a uniform fitness cost to all parasite clones by reducing lifetime transmission potential.

In experimental murine sepsis, blockade of PD-1 or PD-L1 improved survival and in humans upregulated PD-1 expression has been detected and correlated with worse outcome [ 52, 53].