For in vivo imaging experiments, the lack of melanin pigment in these albino mice increased the sensitivity of detection substantially.
While the data presented here addresses the sources of variation in many microarray experiments, the lack of temporal variation in gene expression in our study may only reflect the expression of the metabolic genes.
In our experiments, the lack of iNOS expression in renal tissues of sStx2-treated pregnant rats in combination with a normal renal physiology and histology indicates the inability of Stx2 to affect the mother's kidneys.
In our experiments, the lack of increase in overall levels of β-catenin in the presence of ACY-1215 and MG-132 was surprising.
In the discrete-choice experiments, the lack of imaging data was weighted the same as for studies performed with negative results, supporting the validity of using the scoring system in the absence of imaging data.
Furthermore, in the double-labelling experiments the lack of cross-reactivity of secondary antibodies was tested by omitting the primary antibody for the Kv4.2 subunit and checking the lack of 10-nm gold particles on the labelled structures (e.g. PSDs or in axon terminals for PSD-95 or SNAP-25, respectively).
Given the limited number of females used in these enclosure experiments, the lack of replication (of enclosure treatments), and our inability to determine paternity for a large number of experimental offspring, we are somewhat cautious in our conclusion that the HP ecotype have higher reproductive fitness.
Thirdly, the mean bias of LII and MAI were not investigated in our experiment for the lack of information on LII and MAI boundaries of manual tracing.
Another limit of this experiment includes the lack of preoperative data for von Frey testing; instead, data for naïve littermate controls were used.
As in Experiment 2B, the lack of guidance by the exact object appearing is consistent with participants encoding category-level information rather than object features, a strategy that is in line with the instructions and the most efficient approach.
