In this paper, we propose an integrated approach in which Life-Science knowledge is (i) captured through domain ontologies and linked to Life-Science data analysis tools, and (ii) propagated through rules to produced data, in order to constitute human-tractable experiment summaries.
Following analysis of each run, the Illumina pipeline output was input into the Solexa LIMS (SLIMS) created by the UC Davis Bioinformatics Core at the Genome Center so that all the images, sequence files and experiment summaries could be examined.
In the experiments, the Summary, Description and Note fields are separately used as queries.
Interestingly, Q-PCR validation/experiments suggests Dok2 and Mrvi1 were induced by TEL-PDGFRB, although both genes were initially identified to be uniquely induced by BCR-ABL in microarray experiments (see summary in Table 5).
That is, do Klf7 knockout effects look like a low-expressing Klf7 strain, and do Klf7 overexpression effects look like a high-expressing Klf7 strain? Figure 4 is also confusing as it appears to combine the knockout and overexpression experiments into summary scores.
In summary, Experiment 2 showed that participants accurately decoded color-object assignments, even though there were extensive one-to-many and many-to one mappings.
Based on the one-year data collected by the experiment, a statistical summary of fading occurrences and their correlation with solar flares, as well as the distributions of time-scales and magnitudes of such events are presented.
In summary, Experiment 1 provided evidence that participants approached interpreting the color-coding system in our task as a global assignment problem; they determined which assignments between colors and objects optimized the color-object associations of the entire set.
In summary, Experiment 2 confirmed our predictions of a hierarchical and segmented organization with distinctive frames of reference based on the salient landmarks (reference points).
