Exact(3)
At the same time, it made an earlier start of the experiment impossible as fish size was too close to zooplankton size and it was impossible to choose a net with a mesh size that would keep the fish inside but allow zooplankton to pass.
For example, when the GAL80[ts] system was tried in order to induce excess CF2 after IFM development was complete, the higher temperatures required caused a decrease in IFM structural genes of control flies, making such an experiment impossible to interpret (data not shown).
Unfortunately, RAP1, HSF1, and FHL1 are all essential genes in yeast, making the simple knockout experiment impossible (Winzeler et al. 1999).
Similar(56)
Although removal of maternal Spt5 will allow the test of this hypothesis, it may potentially lead to early death of embryos, rendering the experiments impossible to carry out.
We were concerned that such cryptic initiation would make the in vivo experiments impossible.
However, the high levels of stable maternal proteins make clean knock down or knock out experiments impossible in most cases, which has led to a heavy reliance on dominant negative approaches.
However, the tetraploid nature of the Giardia genome makes such experiments impossible to conduct as it will never be possible to delete all four copies of the endogenous glsec61α gene.
That is because any rigorous, scientific, controlled experiment is impossible — especially one involving a suitably large sample of whole nations.
Attempts by other writers (Flaubert, the Goncourts, Zola) to establish a more genuinely realistic form of theatre failed, partly because public taste and theatrical commercialism made experiment nearly impossible and partly because the plays written were theatrically incompetent.
If the key experiment is impossible (perhaps the necessary reagents or technology are not available), the author may simply submit the manuscript elsewhere and try their luck with a different set of reviewers or a journal with a different philosophy of what is "interesting".
3) Figure 4C, lanes 1-4: this is a confusing experiment and impossible to interpret.
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