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We set up a full-scale Design of Simulation Experiment (DoSE) using the Discrete Element Method (DEM) to investigate the influence of various process parameters (the spray rate, the number of nozzles, the rotation rate and the drum load) on the coefficient of inter-tablet coating variation (cv,inter).
The combination of all three factors in this experiment (dose level, number of doses, and tissue) has provided us with a greater ability to focus on the gene expression changes that appear to be due to or in response to methapyrilene-induced liver injury.
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For each experiment, dose-response curves were performed for each single chemotherapeutic drug and in combination with the miR-21 inhibitor.
For this experiment, doses of glibenclamide were administered every 24 h for 7 days.
Experiments studied include simple (CW-XEOL) spectroscopy, (TR XEOL) lifetime experiments dose and dose rate dependence CW-XEOLL) experimentspatialial (TR XEOL) on heterogeneous sample, wavelength resolved (TR XEOL), Optically Derived X-ray Absorption Spectroscopy, (OD XAS).
In five different experiments, dose-dependent chemotaxis of GC B cells was observed (Fig. 2C).
However, in similar experiments doses of other antagonists within this range have proven to be effective [ 31].
NJL carried out the cloning studies, subcellular fractionation, participated in study design, neurosphere experiments, dose-response testing and Western analysis.
In preliminary experiments, doses of LPS used in young adults (5 mg/kg) induced 100% mortality in senescent rats within the first 12 hours of endotoxemia.
Unless otherwise stated, both enzymes were in all experiments dosed to a concentration of 500 nkat/mL of liquid based on the activity of the preparation.
In cell culture experiments, doses of 50 100 μM MSC have been shown to inhibit mouse mammary epithelial tumor cell growth effectively [ 4, 8].
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