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Even the most trivial deviation from a technical protocol culturing cells, quantifying proteins, detecting RNA can make an experiment difficult to replicate.
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This makes long-running experiments difficult to plan or to create.
This condition makes most of the spectra produced by a mass spectrometer in proteomics experiments difficult to interpret.
The discrepancy between a lack of effect on quantitative measurements of Aβ42 and Aβ40, and a significant lowering of plaque burden in the group that received just 2 weeks of tarenflurbil versus 4 months administration in the preventative group, makes these experiments difficult to interpret.
Although all key enzymes are present in mice, it is difficult to compare mice pharmacology with that in human, which makes the comparison of dosages used in this experiment difficult compared to studies in humans.
Results From the Santa Fe Experiment That the city of Santa Fe has effectively become a very large fried-haddock-dinner experiment is difficult to deny.
"The audacity of this experiment is difficult to overestimate," Dr. Fitch has written.
David F. Albertini, an expert on reproduction at the University of Kansas Medical Center, said the result was "a pretty exciting observation" but added that the experiment was difficult to interpret.
However, the Biot number for an interface in an unsteady-state experiment is difficult to determine.
In the case of structures subjected to explosive loading, the load itself is very much uncertain, as it is widely accepted that explosive experiment is difficult to predict.
In fact, the design of the experiment was difficult to understand and the British authorities took advantage of it to promote their own particular interests.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com