On the other hand, when we clustered enrichment scores from GSEA on the dendritic cell data, results were not in agreement with the prediction (Figure 5): our experiment clustered with the GSE8658 data set (response to different ligands), while GSE6965 clustered with GSE7247 (an experiment on loading DCs with different antigens).
It is not unexpected that expression profiles of different time points of the same microarray experiment cluster together.
This program provides a biological interpretation for the lists of under- and over-expressed genes generated by a microarray experiment, clustering functionally synergistic genes into Gene Ontology (GO) categories.
As HAC1 expression is upregulated with μ in our experiment (cluster 6 in Fig. 2) as are its primary targets, we can conclude that UPR induction with increasing specific growth rate is one major regulatory reaction to increasing cellular proliferation.
For the main analysis, one-stage individual participant data meta-analyses taking into account experiment clustering using binary logistic regression models (no analogue flashbacks vs. analogue flashbacks) were performed.
Indeed, in their lineage-discrimination laboratory experiments, clusters of trophozoites from each Entamoeba aggregated at a distinctive rate, density of cells per cluster, and distance among clusters.
In initial experiments, clusters of cells known as islets from the human pancreas were either exposed to small proteins that cause inflammation or infected with the Coxsakievirus.
In all transplant experiments, clusters of CrxGFP cells survive in the sub-retinal space and the RPE remains detached at sites adjacent to the clusters (Supplementary Material, Figs S3 and S5C).
Interestingly, roughly one third of the genes that were downregulated more than 2-fold in one or both CATMA microarray experiments cluster in a genomic region of approximately 84 kb upstream of RLK902.
First, experiments clustered together should be similar, and those clustered separately should be dissimilar.
