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Sucker Punch is a monument of crassness – a live-action anime culled from early Britney videos, something like a Shutter Island for catwalk models and jointly scripted by the Marquis de Sade, Tarantino and Bertolt Brecht, all experiencing off-days as a result of magic-mushroom poisoning.
So naturally I figured I'd be experiencing off-key voices, patchy dialogue, and terrible dance moves.
The odds of experiencing off-time were approximately 30% (Physical Functioning subscale) to 50% (Mobility subscale) higher for patients with a 1-point higher score.
Known-groups validity analyses indicated that scores on the Revised SCOPA-DC were lower among patients who reported experiencing off-time when compared to those without off-time.
Mean scores on all three subscales of the Revised SCOPA-DC (Table 4) were lower for patients who reported experiencing no off-time than for patients who reported experiencing off-time on a normal day, at baseline.
The literature review indicated that non-motor symptoms have a strong impact on the HRQOL of PD patients [ 39- 42], and that they are associated with experiencing off-time [ 19, 21].
Patients believed they could reliably tell when they were experiencing off-time, and that their physicians and nurses had taught them about off-time early on in their treatment.
Nevertheless, patients whom reported experiencing off-time at baseline, did have, on average, higher SD values in all three subscales, than patients without off-time, with two of these differences being statistically significant.
The first 3 focus groups were used to assess the original SCOPA-DC for comprehension and validity, obtain general information on patients' experience with PD symptoms, including their ability to identify when they were experiencing off-time, and to elicit non-motor symptoms considered to be important to patients with off-time.
Significance testing was not conducted if the sample size was less than 5. Longitudinal binary logistic regression using generalized estimating equations (GEE) [ 38] was used to assess the relationship between single-period scale scores and the probability of experiencing off-time.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com