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In group A, all 12 patients experienced aggravation within 8 months.
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More than 50% of ametropic pathologists had experienced an aggravation of ametropia during their work in pathology with a median aggravation of 1.5 dioptres.
Many of us have experienced the aggravation of being stranded at an airport.
Here's the other thing: almost every journalist has experienced the aggravation of having readers give aggrieved, enraged, dismissive, or, really, any other type of negative reaction to an article based solely on a headline.
Two retrospective studies reported that 24 35% of women with migraine experienced an aggravation, 5% an improvement and 44 65% no change in their migraine during treatment with contraceptive pills [79].
Other media reports highlighted disillusioned patients of homeopaths who didn't get cured of their condition or of those people who experienced an aggravation of symptoms.
Two serious adverse events were reported (one patient had a gastric haemorrhage and one patient experienced an aggravation of her rheumatoid arthritis), but both were felt to be unrelated to the trial medication.
Half of the 18 patients experienced homeopathic aggravations, one experienced an apparent "proving" symptom and several seemed to respond to later remedies but not to earlier remedies.
Around menopause, some women experience an aggravation of their migraine [69].
It has been known for a long time that some female asthmatic patients experience an aggravation of asthma symptoms during the premenstrual or menstrual phases of their cycle.
However, clinical experience suggests that if this therapy is then tapered off and stopped, some patients experience clear aggravation of symptoms and signs, indicating that the beneficial effect was still present before tapering.
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