Study sites differed considerably in terms of clinical trial experience, laboratory testing experience and even availability of laboratory infrastructures.
However, regardless of the level of experience, laboratory operators and pathologists showed significantly lower accuracy in interpreting the difficult results than the obvious results for SD Bioline (indicated in "#" in Figure 2).
Many faculty commented that students often learn skills "somewhere else"—a research experience, laboratory sessions, upper-division classes other than in an introductory course.
Laboratory confirmation based on MAT is a much delayed process, and it is technically challenging, requiring experience laboratory scientists to perform the tests, and the maintenance of live leptospira cultures.
Perez et al. [ 11] have shown the importance of using high-volume, experienced laboratories for HER2 testing to improve the process of selecting patients likely to benefit from trastuzumab therapy.
In this panel, 10 myeloid cell subsets, representing known or potential MDSC subsets, are evaluated simultaneously by 23 experienced laboratories in Europe and the US, thus representing the most extensive MDSC analysis undertaken so far.
Ten experienced laboratory employees volunteered for the study.
Experienced laboratory technologists, blind to the reference classifications, processed the studies and manually corrected the automatic left ventricular positioning within each software package when necessary.
These strategies require dedicated laboratory equipment and experienced laboratory-trained operators.
In addition, the technique is laborious and requires experienced laboratory technicians, both for the staining and for the reading of the slides so that often, in field conditions, its sensitivity is even lower than expected [7], [8].
