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At a macro-level, Zhao et al. [ 15] reviewed performance indicators for Global Fund malaria programs and identified an over reliance on input indicators especially those related to training activities at the expense of outcome or impact indicators, which are better suited to measuring disease reduction.
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Exclusive focus on the implementation and monitoring of program outputs, at the expense of monitoring outcome and impact, has compounded this problem.
The current analyses revealed, with small to moderate effect sizes, that across the three levels, the outcome deteriorated with longer follow-up periods (>10 years) in the EOS samples, but the association was rather curvilinear in the MIX samples with both "good" and "poor" outcomes increasing at the expense of "moderate" outcomes with longer follow-up periods.
26 51 60 In line with this lack of patient-centredness and similar to our findings, symptom outcomes and adverse effects are most frequently included in preference studies, at the expense of other outcomes.
Secondly, it is important to ensure that improved metabolic control is not achieved at the expense of psychological outcomes.
Groups such as Genewatch UK express concerns about the costs of products, or that commercial involvement may skew research agendas towards commercially viable products at the expense of other outcomes that may be of importance [ 53].
Everyone loves optimism but even this good vibe can go too far when it enters the realm of magical thinking and hopefulness at the expense of realistic outcomes.
Limiting the number of score variables to allow for easy score computation comes at the expense of accuracy of outcome prediction.
To demonstrate this we adopted a cost-minimisation approach that ensured any reduction in cost was not at the expense of a poorer outcome.
However, timing is important in this and experts have pointed out that, in primary care, focussing solely on symptoms and function may create incentives for healthcare providers to focus on short-term gains at the expense of longer-term outcome [ 33].
What some see as overregulation relative to food choices in schools or the size of sodas relative to sugar, I see as potentially a way of saving citizens the expense of negative health outcomes including cancer.
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Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com