Drug approval processes require extensive testing and have recently put more emphasis on understanding mechanistic drug action in the body including toxicity and safety.1 Consequently, there is an urgent need in the pharmaceutical industry to develop mechanistic pharmacokinetic (PK) models able to both expedite knowledge gain from experimental trials and, simultaneously, address safety concerns.
For example, if one centre's ideas for improvement are currently implemented elsewhere, sharing resources and experiences may both facilitate and expedite knowledge translation.
The rapid development of e-commerce has expedited knowledge growth in the e-commerce social community.
In fact, they could benefit from sending labor abroad if it meant expedited knowledge transfers from host countries.
Mimetics of the interaction sites of well-known molecules have been successfully built [ 274, 275], the process of which could be significantly expedited by the knowledge of putative interaction sites, as it would allow rational construction of a mimetic compound without requiring mass screening.
"These are kids who want to return and their parents want them to come home, because they were essentially tricked and there's been no effort to our knowledge to expedite the return to their parents," said Valdes, noting that her organization is working on at least three such cases.
This group will build upon an assessment of CDS-related federal agency activities conducted in 2007 to leverage collective efforts and knowledge to expedite development and adoption of effective CDS capabilities.
Together with reference DNA panels, this information facilitates training, certification, and development of new tests and knowledge that may expedite the eradication of sheep scrapie.
Combined with reference DNA panels, these resources facilitate training, certification, and the development of new tests and knowledge that may expedite the eradication of sheep scrapie.
The minimal computational expertise that is required may be prohibitive for many experimentalists, denying them access to this knowledge that could expedite their investigations at the lab bench [ 33].
This review documents the context in which CR must be considered, before comparing the relative efficacies and bottlenecks of potential technologies, expediting identification of the major knowledge gaps and future research requirements.
