Sentence examples for expected to destabilize the from inspiring English sources
Oxidative chain cleavages are expected to destabilize the spatial order of cellulose chains in crystalline material.
The Y470H mutation is expected to destabilize the YYY motif by impairing both the Y470-Y548 and Y470-Y551 interactions, whereas the Y548H and Y551H mutations are expected to partially reproduce the effect of Y470H, as they only impair one of the Y470-Y548 and Y470-Y551 interactions.
The resulting repulsive interactions would be expected to destabilize the ternary complex.
The E715K mutation introduces a repulsive electrostatic interaction with K702 and is expected to destabilize the αC-helix "in" conformation.
Structural perturbation of the DH fold is expected to destabilize the masking of the distal RAS binding site.
All of these mutations are expected to destabilize the extracellular IG domain of β1 and result in loss of function.
Therefore, the Y254V mutation might be expected to destabilize both the pre-translocation and post-translocation states in binary complexes, leading to increases in r1 and r2.
In the MPDNN calculation, temperatures were set to 30°C higher than the actual hybridization temperatures because the hybridization buffer contains 50% formamide which is expected to destabilize duplexes in a way equivalent to increasing the temperature by this amount (0.6°C per 1% formamide) [ 37].
Second, layering mechanism, where new rules are attached to existing ones, is typically expected to destabilize existing institutions but can also decrease the push for broader change by layering regulation only for a particular segment.
Whereas all mutations reported earlier are expected to destabilize Gigaxonin by interfering with its homodimerization, its interaction with Cul3 or by impairing the proper folding of either the BTB or the KELCH domain, the mechanism of instability of Gigaxonin mutated at residue E486 may differ.
Some of these are anticipated: for instance, sterically unfavorable purine-purine mispairs such as A·G are expected to destabilize duplex DNA more than purine-pyrimidine mispairs.
