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Oral medication yielded plasma levels far below those expected to be efficacious.
Thus Treg transfer therapy is expected to be efficacious for UC.
The total in vitro lung doses of the phages, delivered from a single actuation of the inhaler, ranged from 107 to 108 pfu, levels that are expected to be efficacious in vivo.
The efficacy of CR6261 in preventing these clinical signs in the prophylactic and therapeutic ferret model presented here, together with the efficacy shown in mice after lethal challenges with different viruses, strongly indicate that CR6261 can be expected to be efficacious against disease caused by the other, less virulent viruses it neutralized in vitro [1].
Furthermore, it must have been demonstrated, with aid of adequate animal studies, that the device is expected to be efficacious.
The fever resolved after treatment with antimalarial drugs and ceftriaxone; neither would be expected to be efficacious for R. felis infection.
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The results of the network meta-analysis showed that abatacept is expected to be more efficacious than placebo and show comparable efficacy relative to the other biologic DMARDs in combination with MTX.
The analysis of HAQ CFB at 24 weeks and 52 weeks showed that abatacept in combination with MTX is expected to be more efficacious than MTX monotherapy and is expected to show a comparable efficacy relative to other biologic DMARDs in combination with MTX.
To facilitate clinical trials of disease-modifying therapies for Alzheimer's disease, which are expected to be most efficacious at the earliest and mildest stages of the disease1,2, supportive biomarker information is necessary.
Despite the not infrequent occurrence of small population sizes where drift would be expected to be most efficacious, random genetic drift was considered an irrelevant evolutionary force in ecological genetics because natural selection was viewed as being particularly strong during periods of population decline.
Abatacept is expected to be less efficacious than tocilizumab, but showed findings comparable to all other biologic agents.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com