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As expected, sensitivity in the first year was higher than that in the second year (82.9 vs 61.5%, respectively, RR=0.45; 95% CI=0.16 1.23).
Our method estimates the minimal necessary number of replicates to achieve an expected sensitivity in the differential gene expression analysis.
As shown in Figure 4, some probes identifying hypersensitive sites in HeLa cells stay unchanged in the other cell lines (probes S9 in HEK293 cells, S6 in S97 cells) and two of the probes not showing the expected sensitivity in HeLa cells (S3 and S4) do show sensitivity in HEK293 cells.
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Emulsions with varying expected sensitivity towards in-mouth coalescence were engineered, sensorially evaluated using a trained QDA panel and physico-chemically characterised using light scattering and microscopy.
We therefore treated specimens from Patients 2 and 3 with TRAIL and/or ibrutinib (or staurosporine as control) and found the expected sensitivity to TRAIL in the pre-treatment samples and resistance in the relapse samples, confirming the role of del 8p) in protection from TRAIL-induced apoptosis (Fig. 5d and Supplementary Fig. 6).
Physico-chemical characterisation of those in vivo and ex vivo processed emulsions confirmed the expected sensitivity of these systems towards in-mouth coalescence.
Relative to this baseline, we expected sensitivity to improve (smaller JNDs) in asynchronous conditions, in which sounds would pull the two lights further apart due to temporal ventriloquism.
This is in addition to the expected sensitivity to UV (Ultraviolet) radiation.
As expected, sensitivity increases with increasing coverage.
As might be expected, the sensitivity in the abdominal cavity depended on the site of the lesion.
Design of sampling strategies is thus dependent on the expected test sensitivity in the study population, which can be measured with MES.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com