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We had planned to enroll 80 participants in the study but a larger than expected screen failure rate and financial and time constraints resulted in enrollment of smaller number of 69 participants.
Because for 8 genes, one dsRNA gave the expected screen signature but the other did not, the non-signature dsRNAs are likely false negatives.
The clinical team should estimate and document the expected screen failure rate, and when projecting number of patients it will be necessary to screen, keeping in mind the difference between the percentage of patients deemed ineligible due to the test and the overall clinical study screen failure rate.
Similar(56)
As expected, screen-detected cancers had the best survival, as they have been downstaged and are subject to lead time and length biases (Miller, 2013).
As expected, screen-detected diabetes fasting plasma levels were elevated in people with IGR and more elevated in people with screen-detected diabetes.
As expected, screening rates for low- and moderate-risk patients were lower still.
As expected, screening sensitivity is higher for women with less dense breasts.
As we expected, screening attendance was significantly higher in women who have previously attended as those that come for screening at first call are more likely to come back for subsequent routine invitations[ 17].
As expected, screening with the HMMs obtained from Pfam and CAZy resulted both in C. jejuni NCTC 11168 and L. rhamnosus GG in the highest fraction of hits that also displayed a GT-like fold.
[ 5] Some of this levelling off may have been expected: screening causes an increase in detection in the year of its introduction and, as a result, a decrease in breast cancers found in subsequent years.
People expect screens they handle to be touchable, and Nintendo wants the device to be easy to relate to.
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