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As expected, rates of hypoglycaemia were higher among participants assigned to intensive glycaemia therapy than in those on standard therapy.
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Recorded diagnoses were used to calculate rates of hypoglycaemia, and the study disregarded multiple diagnoses of hypoglycaemia in the notes.
We are therefore also recording rates of moderate hypoglycaemia in an attempt to increase power and identify the ability of pumps to reduce rates of hypoglycaemia.
Likewise reduced rates of hypoglycaemia have been reported of glucosidase inhibitors [ 4].
A plethora of secondary end points were assessed, including rates of hypoglycaemia.
This may cloud comparative interpretation of data such as rates of hypoglycaemia, as hypoglycaemia is sensitive to attained levels of A1C.
Since our database did not systematically capture minor hypoglycaemia not requiring admission, under-estimation of true rates of hypoglycaemia was likely.
Secondary outcomes included changes in HbA1c, BG profiles, weight, insulin dose and rates of hypoglycaemia.
Rates of hypoglycaemia and weight change were comparable between the two treatment groups.
We aimed to determine incidence rates of hypoglycaemia in type-2 diabetic patients and identify predictors of hypoglycaemia when treatment is intensified.
The lack of consensus regarding definitions makes it difficult to compare rates of hypoglycaemia across studies.
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CEO of Professional Science Editing for Scientists @ prosciediting.com