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This may have led to some contamination, resulting in a higher than expected quit rate in the control group.
Smoking cessation after Respiragene testing and estimation of lung cancer risk with telephone counselling in a small pilot study in Auckland NZ (n = 43) compared with expected quit rate.
This rate is higher than the 5% expected quit rate for general population smokers with no help (Hughes, Keely, & Naud, 2004), marginally higher than the 12.3% quit rate reported in a previous review of people with COPD (Hoogendoorn et al., 2010), and lies within the range of general population quit rates in response to behavioural interventions for smoking (Poulsen, Dollerup, & Moller, 2010).
The sample size calculation was based on assuming a level of significance of 5%, a quit rate after brief anti-smoking intervention only (control group) of 5% [ 23], an expected quit rate in the experimental group of 14% [ 20], and a 1 1 ratio of control to experimental subjects.
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