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Thus, Dr. Decker said, "our impression at this time is that there's no material difference in the expected potency or the effect in use between our product" and the vaccine in the federal stockpile, which was produced in the late 1970's or early 1980's.
Interestingly, racemic MDMA appeared to exert a greater than expected potency and/or an enhanced effect on measures such as movement episodes, center actions (entries and distance), clockwise rotations, and jumps; actions that might be explained by additive or synergistic (i.e. potentiation) effects of the stereoisomers.
As the authors point out, however, the lower than expected potency for 3-methyl-2-butenal is related to hindrance imposed by the bulky disubstituted alkene terminus.
Furthermore, diabetes care providers may fail to implement effective therapies due simply to clinical inertia or perhaps a poor understanding of the expected potency or durability of the glucose-lowering therapies that they prescribe.
30 The minimum expected potency for the mumps content was higher in the MMRV vaccine (≥104.4 median cell culture infective dose (CCID50)) than in the MMR vaccine (≥103.7 CCID50).
Since the need for fluids is difficult to assess objectively, the choice to give fluid instead of vasopressors or inotropes may depend on the expected potency of the fluid.
Similar(54)
The minimum expected potencies for measles, rubella and varicella were identical between the MMR+V and MMRV vaccines.
We positively identified all of these known ligands with our assays, with expected potencies confirming the utility of these NR assays.
All concentrations for time courses and dose responses were chosen based on our previous studies (Jeng et al. 2009, 2010; Jeng and Watson 2011; Kochukov et al. 2009) that demonstrated expected potencies, efficacies, and rapidity of the responses.
As expected, the potencies were reduced with the huIgG1-mutant likely due to reduced FcγR interactions with peripheral blood mononuclear cells (PBMCs), and with the Half DVD-Ig format likely due to monovalent binding for T cell activation.
However one may expect that potency is important to prediction and may contain useful information.
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