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The differential genomic feature overlap analyses of eQTMs were done by comparing the number of observed overlaps for positive and negative eQTMs, with the number of expected overlaps in non-eQTM sites.
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Because of the expected overlap in the patterns of gene expression in the glomerulus gene set with the normal cortex, we focused our analysis on the cortex gene set.
Regarding the first issue, parent-offspring conflict over mate choice in contemporary Western populations has been found to contain considerable conflict of interest, as well as some expected overlap, in preferred attributes [28] [31].
These studies did not, however, investigate the expected overlap in cortical activation due to the stimulation of different fingers.
With low power, the expected overlap in sites predicted to be under selection would also be low [ 19].
Model-based methods may conform better with the expected overlap in biological cell subpopulations, but do not normally scale well to very large datasets, and have a high computational load.
However, we expect overlap in the description of chemical structure by various groups of descriptors.
Although stratified sampling is commonly used to organize the units of observation naturally distributed over non-overlapped strata, such as geographical regions (Thompson 2012), the expected overlapping of subjects in the context of social networks groups can suggest some affinity among them, supporting the re-organization of the sampling frame into a smaller set of groups.
When we take the top 500 genes with increased variability in U-CLL in each dataset (see Additional file 1), we find a significantly higher than expected overlap (69 genes in both lists, Hypergeometric test, P value <2.2e-16 <2.2e-16
To score k-mers, the expected overlap for co-occurrence in syntenic pairs were calculated from single genome frequencies.
Second, of the 28 Mec1/Tel1-dependent and Rad53-independent phosphoproteins that were induced after exposure of wildtype and rad53Δ yeast to methyl methanosulfonate, 7 were present in our list (expected overlap of 1.787 proteins, p = 2.575e-04) [ 12].
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