Your English writing platform
Discover LudwigExact(9)
However, Nocturnin is acutely induced by the absence of the expected meal in eWAT of restricted fed mice.
To test the affect the absence of the expected meal would have on Nocturnin expression, mice were habituated for 7 days in cages with running wheels placed in 12∶12 LD with ad libitum access to standard chow.
When summed over the two hours following expected meal time, high intensity activity for mice that had previously received once daily high fat treat was significantly greater than that for mice fed ad-libitum on the first and second day of withdrawal, while food bin entry was significantly increased on the first day of withdrawal but not on the second day (Fig. 11H, 11J).
Interestingly, when the daily high fat meal was not delivered, the female mice reacted by subtly increasing activity and food bin entry at expected meal time for two days, suggesting that these mice did indeed anticipate food arrival (or were entrained rhythmically) but did not express anticipatory activity or food bin entry.
To test whether peak expression was dependent upon the presence of the expected meal in this paradigm, we placed animals on a restricted feeding schedule for 12 days and on the thirteenth day no meal was presented at ZT3 (Figure 4A).
The observation that Nocturnin expression is not acutely induced by food nor by the absence of the expected meal in the livers of restricted fed mice suggests that the regulation of Nocturnin expression in the liver is likely the result of the local circadian clock, a food entrained oscillator, a systemic cue that is not dependent upon the daily presentation of food, or some combination thereof.
Similar(51)
Of course, it was even worse than I expected — meals at McDonald's and runs in my hose were the least of it.
Thus, our observations are consistent with the expected meal-associated hormonal changes, with no significant differences between the H. pylori-positive and -negative subjects, as well as when data were normalized (Additional file 3, Table S5).
Following H. pylori-eradication in subjects previously colonized with cagA-positive strains, the expected meal-associated increase in PP was significantly lower than expected (27% vs. -13%; p = 0.01).
As he settled into the Malheur National Wildlife Refuge, and told the cameras that anyone who wished to join him could expect meals and a warm bed, he laid out his plans.
Chelsea, denied their expected easy meal, were left to ponder the implications of another ruinous defeat in a bewilderingly traumatic season.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com