Suggestions(1)
Exact(4)
Reproducibility based on the weighted kappa coefficients showed expected level of agreement and was almost perfect in case of 8 questions, substantial for 5 questions and moderate for 2 questions.
The lower than expected level of agreement between these two indices may also reflect the inclusion of several Instrumental ADLs (e.g., meal preparation, housework, managing medications) in the Armstrong (but not the Full Frailty) index.
Attempts at linear modeling, performed as a meta-analysis comparing ratios from the different methods using the metafor R package [ 34], did not return the theoretically expected level of agreement between observed allelic ratios from any alignment methods when compared against SNaPshot in either cDNA synthesis method (data not shown).
Since both observed agreement proportions and expected agreement proportions were equal to 1, the Kappa (agreement above that expected by chance) is either 0 or undefined; providing little information on the expected level of agreement.
Similar(56)
As expected, the level of agreement between the presented method and DESeq correlates with the number of timepoints where DESeq identified genes to be differentially expressed.
As expected the levels of agreement between PAL2 and behavioural mapping increased for the categories of lying and sitting (see Table 2).
The kappa values range from -1 to +1: values between -1 and 0 indicate that observed agreement was lower than that expected by chance, 0 indicates a level of agreement equal to that expected by chance, and +1 indicates total agreement.
The Fleiss' kappa can be computed from this matrix (see example below) to show the degree of agreement between the psychiatrists above the level of agreement expected by chance.
Finally, adolescents 19 21 years old would be expected to show a lower level of agreement than the rest of age groups.
κ can range between 1 (perfect agreement), and 0 (level of agreement expected by chance alone); κ > 0.80 is considered to reflect almost perfect agreement, κ between 0.61 and 0.80 substantial agreement, 0.41 0.60 moderate agreement, 0.21 0.40 fair agreement, and κ < 0.20 poor agreement [ 26].
As expected, the level of intra-observer agreement was higher than the inter-observer agreement.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com