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But when the chimps developed kuru two years later, Dr. Gajdusek theorized that a slow-acting virus was at work, somehow not producing the expected immune reactions.
Hence, neutropenia remains a transient and expected immune dysfunction.
As expected, immune plasma to both immunogens reacted with 3D7 DBL5 recombinant protein, but only the anti-DBL1-6 plasma reacted with 3D7 DBL1 recombinant protein (Figure 1), indicating that multiple domains were targeted in the full-length immunogen and that antibody epitopes were not shared between the DBL4-6 domands anDBL1L1.
Dosing regimens can be optimized on the basis of the expected immune responses.
As expected, immune cells were also present throughout the stromal regions.
Pricking infection provides the expected immune gene activation, resulting in induction of Toll and IMD pathways that lead to strong AMP expression.
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As expected, immune-reaction for GPIHBP1 was co-localized with the endothelial marker CD31 and also with LPL.
If evolution on remote, parasite-impoverished islands necessarily leads to increased susceptibility to exotic parasites, then we might expect immune responses to be uniformly lower in island populations relative to their mainland counterparts.
This may be due to the nature of our samples - we might expect immune system genes to be highly expressed.
The maintenance and use of an immune system does not come without energetic costs; and therefore we expect immune systems to have evolved different responses to the costs and benefits of defense under different conditions.
Although many of them are interfering with immune cell function, a secondary effect on lymphangiogenesis is expected, as immune activation induces lymphangiogenesis by different factors mentioned above.
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