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Ever since, these changes are either considered a pathologic syndrome with clinical significance (formation of nociceptors at the level of interspinous contact) or a part of expected degenerative changes occurring with increasing age [8, 9, 10, 11, 12, 13, 14, 15].
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One might expect any degenerative changes to be worse in the root than in the arch but the protected aortic root in this patient had normal histology.
Consequently, we would have expected them to have less degenerative changes.
To study the selective vulnerability to frataxin deficiency in a model where no confounding non-specific or secondary degenerative changes are expected to occur, we have utilized frataxin-deficient mice to investigate gene expression profiles in the heart, a major target of FRDA pathology, and in skeletal muscle, only sub-clinically affected in the human disease.
As expected, the mean age for patients undergoing surgery for spinal stenosis and degenerative changes (N = 10, 17%) was higher (M = 65.7, SD = 6.61).
Patients undergoing lumbar spinal surgery for degenerative changes and/or herniated disks were chosen because they were expected to make at least some symptom and functional improvements by 3 months postoperatively.
As expected, the most recurrent diagnoses were part of the non-specific back aches category, at 66.9% and 65.1%, and the probably degenerative changes category, at 18.5% and 17.2%, for 2000 and 2007 respectively.
It has produced degenerative changes in the liver and kidneys of experimental animals.
c Degenerative changes.
Unfortunately, postoperative degenerative changes occur.
c Degenerative changes of Oral sucker (Os).
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