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Samples retrieved from the zebra carcass contained, as expected, cells of B. anthracis.
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As expected, cells deleted of Pkc1p are also sensitive to CFW and this can be observed already at a concentration of 50 µg/ml.
As expected, cells depleted of KIF1C displayed fragmented Golgi complexes that very likely represent peri-nuclear mini-stacks.
As expected, cells expressing high levels of HPRT have a histone modification pattern at the promoter consistent with active transcription.
As expected, cells expressing low levels of EGFR and HER2, GI101A, MDA-MB-435 showed least growth inhibition.
Thus, the DNA methylation profile based on the EShypo-T-DMRs reflects the characteristics of the expected cells.
Testing for differences in outcome variables between CWP and CLBP patients was done using chi-square tests (for categorical data with expected cell frequencies of n ≥ 5), Fisher's exact tests (for categorical data with expected cell frequencies of n > 5), t-tests accounting for unequal variances (Welsh tests), and Mann–Whitney U tests (for ordinal data).
The toxicity exponent for intensified therapies (see Eq. (3)) is 0.80 for tumour cells and 2.44 for effector cells leading to an expected cell kill of 95.0 %, respectively, and 62.2 % for intensified Etoposide therapies.
Samples containing 0% and 100% viable cells showed a significant difference to the expected cell count of 5*107 cells/ml and were in a range between 5.57 * 107 - 6.65 * 107 cells/ml.
In the case of small samples where the chi square test was compromised (more than 20% expected cell count of less than five), the Fisher exact test was used.
In case of expected cell counts less than five, the Fisher-exact test was used.
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CEO of Professional Science Editing for Scientists @ prosciediting.com