Sentence examples for expected binding sites from inspiring English sources

In this method, the Binding Site Protocol generated a number of expected binding sites.

Motifs a4 and a15 had significant hits to known TFBS which were different to the expected binding sites.

Promoter analysis of sequences in the training set identified three of the five expected binding sites for muscle-specific transcription factors.

The crystal structure shows that Ap5G locks an incompletely closed conformation of the enzyme, in which the adenine moiety is located outside its expected binding site.

Remember that the ratio λ/μ predicts the expected binding site number in stochastic equilibrium.

If, however, the lineages are separated for a long time and differ in their expected binding site densities, the V/m ratio can be larger than 1.

The expected binding site of compound 8 was successfully confirmed by demonstrating chemical shifts in the H N HSQC spectra for residues at the pVHL-HIF-1α interface as a result of compound titration.

Motif analysis was performed by using CisFinder tool (Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, NIH, Baltimore, MD, USA) [ 43] on 200-bp sequences centered at the expected binding site indicated by peak summit calculated using the MACS tool.

The structure of Ro48-8071, whish is an orally active inhibitor of human hepatic OSC, has been determined in complex with the squalene-hopene cyclase (SHC), the prokaryotic counterpart of OSCs, responsible for the conversion of squalene into cyclic compounds in bacteria, and it is suggested that Ro reacts with the expected binding site for squalene.

However, van Nimwegen et al. [10] (supporting text) use a simple maximum-entropy argument to show that the additivity assumption on energy does imply the PWM model for binding sites, if one also makes the reasonable assumption that binding sites have a significantly higher expected binding energy than random sites.

Naphthalene-sulfonic acid derivatives were found to bind to arginine only, as opposed to expected binding to all basic sites (Arg, Lys and His).