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One of the reasons why antibodies have such good binding parameters is that in vivo they are subjected to rounds of expansion, selection and mutation which allow them to evolve with repeated exposure to the challenging agent.
Travis & Dytham [14] have recently produced a model that suggests that during range expansion selection may favour individuals with a higher propensity for dispersal.
The architecture of natural variation present in a contemporary population is a result of multiple population genetic forces, including population bottleneck and expansion, selection, drift, and admixture.
Lower than expected polymorphism frequencies at synonymous sites may reflect demography (population expansion), selection at linked sites or purifying selection on the sites themselves.
Harvest, isolation, activation, transduction, expansion, selection and cryopreservation of patient-derived T cells to produce bespoke medicinal therapies requires notable infrastructure and expertise.
In the GC, clonal expansion, selection and differentiation of GC B cells result in the production of high-affinity plasma cells and memory B cells that provide protection against subsequent infection.
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The expansion selections were the highlight on the first day of a three-day convention in the Saddledome.
During range expansions selection may favor the evolution of higher dispersal, and symbiotic interactions may be affected.
A negative Tajima's D signified an excess of low frequency polymorphisms, indicating population size expansion, purifying selection, recent directional selection and/or background selection of deleterious mutation.
For example, population expansion, purifying selection or selective sweeps may result in an excess of rare variants [ 51, 52].
Labour is fighting a bitter leadership battle but senior figures from across the party united to oppose the expansion of selection, with Hilary Benn, whose sacking by Jeremy Corbyn kicked off mass resignations over the summer, supporting Rayner's stance from the backbenches in the Commons debate.
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