Sentence examples for expansion of endogenous from inspiring English sources

Pharmacologic expansion of endogenous β-cells is a promising therapeutic strategy for diabetes.

While a variety of potential replacement therapies are being explored, expansion of endogenous insulin-producing pancreatic islet β-cells remains an attractive strategy.

The kinetics of expansion of endogenous bearing T cells in allogeneic hosts strongly supported this hypothesis.

However, while there was no significant expansion of endogenous pentamer+ cells in both groups of mice (Fig. 4b), there was high level virus replication in CD62L- T cell transferred, but not in CD62L+ cell transferred recipients.

Subcutaneous inoculation with influenza WSN-gB virus resulted in maximal expansion of endogenous glycoprotein B (gB -specific CD8+ T cells at five days after infection in the popliteal lymph nodes (FigB -specific seven days post-infeCD8+n in The spleen (Figure 1B).

We next examined whether liver-primed CD8+ Treg cells could regulate the expansion of endogenous CD8+ Teff cells in vivo.

In later stages an expansion of the endogenous horseshoe-shaped expression domain is also found (data not shown).

Hoxb4 also shows ectopic expression in animal cap ectoderm and expansion of the endogenous expression domain (Fig. 2B), but no closure of the dorsal expression gap neither in organiser mesoderm nor in overlying ectoderm can be observed.

Given the relatively fast onset of protection, the lack of evidence for newly generated neurons, the expression by NSCs of cytokines that protect neurons (e.g. sonic hedgehog), and the close physical association between the NSCs and neurons, it is possible that the expansion of the endogenous NSC population results in increased neuroprotection by trophic support.

Whether these Tregs represent a de novo generated population from naive precursors or an expansion of the endogenous population is not known.

Together, these findings support the notion that the long-period oscillations observed in Meth-treated animals, and likewise in Slc6a3 −/− mice, are due to period expansion of an endogenous ultradian rhythm of arousal.