Exact(6)
The detection of TBP in intranuclear protein aggregates in brain tissues from Huntington and Alzheimer patients [8] and the association of expanded polyglutamine stretches in TBP with Huntington like symptoms in a Caucasian family [9] have led to the proposal that TBP may play a more general role in a common mechanism for trinucleotide repeat expansion mediated neurodegeneration [8], [10].
The LP gene family has undergone recent expansion, mediated through one distant and several rounds of local tandem duplication events.
We believe the second mechanism is the predominant one in our model as the lymphatic expansion mediated by macrophages was sensitive to VEGFR inhibitors.
Furthermore, in vivo studies indicated that Treg expansion mediated by cancer cell-secreted miR-214 resulted in enhanced immune suppression and tumor implantation/growth in mice.
In the present study we wanted to examine whether selective forces would leave a base compositional pattern in the core genomes of bacterial strains undergoing genome expansion, mediated through HGT, since such a pattern has been observed for microbial species undergoing genome reduction [ 3, 13].
"Polyketide Ring Expansion Mediated by a Thioesterase, Chain Elongation and Cyclization Domain, in Azinomycin Biosynthesis: Characterization of AziB and AziG".
Similar(54)
Marinobufagenin (MBG) is an endogenous bufadienolide cardiac inotrope which is demonstrating growing interest in the early diagnosis of volume expansion-mediated hypertensive states such as preeclampsia (PE) and end-stage renal disease hypertension.
There are multiple components underlying CAG expansion mediate disorders, which involve aggregate-prone polyQ proteins as well as untranslated CAG repeat expansions at the mRNA level.
Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP phosphocholine cytidylyltransferase. Cell Metab.
Martino, M.E.B. et al. Airway epithelial inflammation-induced endoplasmic reticulum Ca2+ store expansion is mediated by X-box binding protein-1.
Xenophagy, for example, also requires Rab proteins for sequestering invading bacteria in autophagosome-like vacuoles (Yamaguchi et al., 2009), consistent with the idea that isolation membrane expansion is mediated by Rab activity.
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