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Since we did not measure plasma volume immediately after resuscitation but waited 2 h in the present study, other more slowly acting mechanisms may have contributed to the poor plasma volume expanding effect of crystalloids compared to colloids.
Knowledge of the volume expanding effect of colloids is essential in many intensive care unit (ICU) patients.
I suggest that the road to rabies control in Africa requires a pan-African approach toward establishing sound surveillance and reporting structures that would enable proper demonstration of the expanding effect of this disease in animal and human populations in Africa.
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In our experiment in healthy pigs, we also found similar differences between the volume expanding effects of RF and HES solutions.
This is a substudy of a prospective, non-randomized, single-center clinical trial, investigating the volume expanding effects of various resuscitation fluids [ 23].
This expanded effect of CD28 and NKG2D co-stimulation was evident only when the assay was performed on negatively selected CD3+CD8+ T cells but not total PBMC (data not shown).
This lack of correlation is interpreted as a result of treatment, and significant correlation between GCS 14 and GCS 21 (r = 0.82; P < 0.007) is interpreted as an expanded effect of treatment to 21 days.
This may suggest that a greater stimulation of acupuncture points is required to elicit these expanded effects; or that the contextual factors within the acupuncture consultation, such as the interaction between the practitioner and patient, or the consultation setting, may work in conjunction with the stimulation of acupuncture points to elicit these expanded effects of care [ 42].
Important factors include the volume expanding effect, risk of pulmonary oedema, cost, and potential impact on haemostasis.
When the proportion of benefit population expanded, the effect of these screening strategies on the long-term costs saving become more and more significant, especially those of universal strategies, exceeding the total costs of the screening program implementation, suggesting a good economic effect in the long term.
Since SRPK1 is usually localized in the cytoplasm in the absence of an extracellular signal and phosphorylates shuttling SR proteins in this cellular compartment [ 33, 34], stress signals might expand the effect of SRPK1 activation to the nucleus and influence also SR proteins that mostly reside in this compartment.
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