Some insight into the role of methotrexate in PsA was provided by the TCR repertoire studies, in which clinical response was accompanied by a significant depletion of the polyclonal nonclonally expanded component of the T-cell infiltrate, whereas the monoclonal expansions persisted, perhaps accounting for the clinical rebound often seen after stopping the drug.
Eighty percent of hemispherical and 57% of peripherally expanded components were considered completely osseointegrated at final radiologic review.
From a morphological perspective, it is worth noting that, in chronic inflammatory conditions such as RA, the expanded lymphoid component of the BM may form follicle-like structures and undergo a localized process of ectopic lymphoid neogenesis.
This posed a unique challenge for Foster as he worked against his own limitations and expanded different components of his style.
Those companies committed to expanding the nuclear component of their production fleets have proved safe, reliable and savvy operators of nuclear power plants, with many employees being nuclear engineers who further honed their skills in the U.S. "nuclear" Navy.
After dispatching naval ships and maritime rescue teams to the region late on Tuesday to help with search and rescue efforts and medical needs, the government on Wednesday substantially expanded the military component of the response.
In 2010, the FCC approved a request from Ligado predecessor LightSquared to expand the terrestrial component of its satellite network, hoping to launch itself as a new mobile carrier.
The biologists have been photographing and studying the area's 300 dolphins, and recently expanded the behavioral component of their project to investigate social structure and complexity (e.g. male alliances), maternal care strategies, and calf development.
In 2006, we expanded the physiological component of this research to include functional genomics (Miller et al. 2011).
Other family-friendly events are by now Tribeca staples: a drive-in theater; a Tribeca-ESPN sports-film festival; and an expanding online component presenting the world premieres of four films and several shorts, along with live-streamed events.
