It has been proposed that Merlin and Expanded are upstream regulators of the SWH pathway, which suppresses Yki-dependent transcription of CycE, DIAP, and Mer/Ex themselves.
The FERM-domain binding motif mediates interactions with several FERM domain proteins, including Yurt, a negative regulator of Crumbs (Laprise et al., 2006), Expanded, an upstream component in the Hippo pathway (Ling et al., 2010; Robinson et al., 2010), the cytoskeletal protein βH-spectrin (Médina et al., 2002), and the cytoskeletal linker protein Moesin (Médina et al., 2002).
Expanding on upstream transcripts, we have recently found that retrotransposon elements (REs) are transcribed in a tissue-specific manner, providing at least 200 000 TSS in the human genome.
Our understanding of PLD1 activation by amino acids has expanded to include the upstream activation of Vps34.
The FTD- and ALS-causing mutation in C9orf72 is an expanded GGGGCC repeat, located upstream of the translation start codon [ 10, 13, 25].
For example, if the annotated interval of genes in the zebra finch genome was expanded by 2,000 bp upstream and downstream then alignments of willow warbler reads overlapped with an additional 1,703 annotated genes.
Sensitivity analysis exhibited that the system boundary of SPA could be narrowed down into the first two upstream stages that contained nearly 50% of energy flow information or expanded toward the first five upstream stages that represented 80% of total energy consumption.
WASHINGTON (AP) — The Army Corps of Engineers proposed on Tuesday a new Southeast water-sharing plan to expand storage in upstream lakes and lower river flows into Apalachicola Bay, Fla.
The country needs to expand operations to upstream products too, to capture a wider market in other TPP countries.
