Sentence examples for expanded indication from inspiring English sources
Gamma-hydroxybutyrate (GHB) is currently authorized by the European Medicines Agency EMAA) to treat narcolepsy with cataplexy in adults, and by the Food and Drug Administration FDAA) to treat cataplexy in patients with narcolepsy, with an expanded indication for the treatment of excessive daytime sleepiness.
Moreover, ESD for expanded indication is reported to be technically feasible from the aspect of short-term outcome [6, 7].
As the lesion fulfilled the expanded indication for ESD according to the Japanese gastric cancer treatment guidelines [3], we elected to perform ESD as recommended treatment.
Although the expanded indication for ESD for the treatment of early gastric cancer is based on the assumption of negligible lymph node involvement, the incidence of lymph node metastasis in cases of early gastric cancer with expanded indication is higher than that in cases where there is an absolute indication for ESD [4].
She received an upper gastrointestinal endoscopy and found to have an undifferentiated-type mucosal gastric cancer with the size of 15 mm in diameter without ulceration, which fulfilled the expanded indication for ESD.
In contrast, studies have reported a comparable low risk of lymph node metastasis in cases with an absolute indication for endoscopic resection, compared to cases with expanded indication [5].
Additionally, improving clinical outcomes and increasing surgeon confidence have also expanded indications to include cases of unilateral visual impairment and paediatric age.
Certain large colorectal tumors satisfy expanded indications for endoscopic submucosal dissection (ESD); however, the resulting large mucosal defects may contribute to complications such as delayed bleeding and perforation.
Prosthesis design and surgical techniques have evolved over time, as have the expanded indications, leading to improved outcomes and decreased complications.
Advances in the design of fixators and bone pins have expanded indications — external fixation as definitive fracture treatment is a real alternative for trauma surgeons.
Advances in the design of fixators and bone pins may have expanded indications and their use as definitive fracture treatment and this may be a real alternative for trauma surgeons.
