Sentence examples for expanded immune from inspiring English sources

Enhancing immune responses by using cancer vaccines or adoptive transfer of ex vivo expanded immune cells has significantly progressed recently and several strategies are already being tested.

Additionally, cytotoxic treatments may distort the tumor architecture, thus facilitating the penetration of the immunotherapeutic agents and the expanded immune population [ 28– 30].

One use of IL-2 is to expand immune cells collected from a patient's blood.

After responding to any neoantigen, contraction of previously expanding immune cell populations is necessary; one mechanism that is used is the induction of apoptosis of activated immune cells – activation induced cell death (AICD).

Indeed, the substantial boost by leaf protein containing p17/p24 protein of Gag-specific cellular and humoral immune responses induced by the DNA vaccine pTHGagC suggests that HIV proteins produced in plants may be very valuable for expanding immune responses after the immune system has been primed.

Using this network and its Boolean rules, we construct the expanded host immune response network shown in Figure 4(a).

Surviving clones expressing the EGFP reporter were expanded, and immune resistance was validated by probing clonogenic survival following incubation with St42Rag2−/− splenocytes.

In summary, by following a network-based pathway analysis, we have expanded the immune-related set of genes associated with MS. Furthermore, we have identified neural pathways whose involvement in the disease is biologically plausible.

In particular, interleukin-15 (IL-15) expands CD8 immune responses in the absence of T cell help, while chemokines attract dendritic cells as well as other professional antigen presenting cells, directly activating T and/or B cells in the periphery.

These observations suggest that mutations towards consensus arise frequently and may be generated continuously during chronic infection, providing a reservoir of replication-competent viruses that can expand once immune selection begins to target majority forms (as was observed in the acute cases studied here).

Despite the efficacy of anti-4-1BB in expanding innate immune cells, as well as host T cells, we found that 4-1BB on the transferred T cells or on the host αβ T cells is necessary and sufficient for the effects of anti-4-1BB on adoptive tumor therapy against the E.G7 thymoma.