Exact(10)
These results are in agreement with the notion that adaptation of H9 viruses to land-based birds can lead to strains with expanded host range.
The results from this laboratory-based adaptation study mimic the ongoing activities of H9N2 viruses in nature and highlight the potential role of land-based poultry in the genesis of influenza viruses with expanded host range.
The continuous circulation of these viruses has had profound ecological and epidemiological implications since they have been involved in the emergence of H5N1 strains with expanded host range with the ability to infect humans and other mammals.
Genotypes 1 and 2 are restricted to humans, and genotypes 3 and 4 have an expanded host range and are capable of causing zoonotic disease (6 – 10 ).
Several lines of evidence indicate that the H5N1 viruses have evolved to more virulent forms since 1997, with different antigenic structure (21 ), internal gene constellations (22 ), and an expanded host range (23, 24 ).
The three divergent nodA genes present in the tropici symbiotic plasmid likely allow CIAT 899, PRF 81 and CFN 299 to have an expanded host range in comparison to rhizobia carrying a single gene.
Similar(50)
These have led to improvements in Bt production, exploitation of Bt gene resources, and development of engineered Bt insecticides and transgenic Bt crops that have expanded host ranges and increased efficacy against target pests.
] We have considered your appeal regarding your manuscript entitled "Immunosuppression enables expanded host ranges and can explain mosaic genome structures in Albugo candida races".
[Editors' note: what now follows is the decision letter after the authors submitted for further consideration.] We have considered your appeal regarding your manuscript entitled "Immunosuppression enables expanded host ranges and can explain mosaic genome structures in Albugo candida races".
[Editors' note: this article was originally rejected after discussions between the reviewers, but the authors were invited to resubmit after an appeal against the decision.] Thank you for choosing to send your work entitled "Immunosuppression enables expanded host ranges and can explain mosaic genome structures in Albugo candida races" for consideration at eLife.
H5N1 virus infection continues to progress with expanding host range and poses a serious global threat [ 8].
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