Your English writing platform
Discover LudwigSuggestions(5)
Exact(51)
The expression level of RORγt in expanded IL-17 producing T cells was significantly higher than in non-expanded cells, while Foxp3 was expressed more strongly in non-expanded cells in comparison to expanded cells, indicating that the IL-17 producing T cells were expanded.
The availability of surrogate markers that can quickly assess the quality of expanded cells make it possible to use the expanded cells immediately without freezing the cells and waiting for the in vivo results.
In that case, concentrated BM presents a number of advantages over expanded cells.
Microparticles can serve as substrates for cell amplification and deliver the expanded cells to the site of the defect.
Freshly isolated cells were found to be homogeneous in cell-size (56.6 ± 7.05 µm²) and deformation (0.034 ± 0.006) thereby clearly distinguishable from in-vitro expanded cells.
Expanded cells were encapsulated in agarose hydrogels, maintained in chondrogenic media for 42 days and analysed to determine their mechanical properties and biochemical composition.
Similar(9)
The bioreactor-expanded cells maintained clonogenic ability and high levels of expression (95.5 99.8%) of characteristic stem cell surface makers, including CD29, CD44, CD90 and CD105.
We performed a phase 1 trial augmenting conventional UCB transplants with ex vivo-expanded cells.
Clinical-scale ex vivo expansion of UCB is feasible, and the administration of ex vivo-expanded cells is well tolerated.
Augmentation of UCB transplants with ex vivo-expanded cells did not alter the time to myeloid, erythroid, or platelet engraftment in 21 evaluable patients.
Recipients of ex vivo-expanded cells continue to have durable engraftment with a median follow-up of 47 months (range, 41-51 months).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com